Suspect and non-target screening of chemicals in household cleaning products, and their toxicity assessment

In this study, 31 household spray-type cleaning products from 10 categories were examined to identify the substances contained in these and evaluate their resulting toxicities. After substance detection via LC-QTOF-MS, suspect non-target screenings performed using UNIFI software. A total of 48 identified during screening. Among them, surfactant (freq. 22/31(71.0%)), plasticizer 23/31(74.2%)), antioxidant 20/31(64.5%)) detected with high frequencies. compounds, tributyl citrate acetate was most frequently (frequency 13/31, 41.9%). addition, 51 analysis. oleamide, a type surfactant, showed frequency (22/31(71.0%)). The toxicities 98 (suspect: 47 (except for confidence level 5) non-target: 51) evaluated European Chemicals Agency (ECHA) database Toxtree. 20 classified as caution. risk assessment 3 references standards also performed. screening technique proved be useful method that can applied when there are many non-specific chemicals components consumer not well known.